PIPERAZINE – 2

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PIPERAZINE
(Intermediate of Ketoconazole)
Chemical Name
1-Acetyl-4-(4-hydroxy phenyl) piperazine
Molecular Formula
C12H16N2O2
Molecular Weight
220.27
Characteristics
Pink to gray crystalline powder, sensitive to light
Melting Range
180O to 185OC
Transmittance
Not less then 85.0% [10%w/v in DMF at 400 nm in 1cm Cell]
Chromatographic Impurity
Total sum of impurities less than 2.0%
Assay by titration
98.0% to 102%
Bulk Packing
Packed in double walled sealed HDPE/PVC bags enclosed in fiber / HDPE drums
Drums
25 / 50 Kgs.
Storage
Store in cool dry place