PIPERAZINE – 1

5

PIPERAZINE
(Intermediate of Itraconazole)
Chemical Name
2,4-Dihydro-4 [4-(4-hydroxy phenyl)-1- piperazinyl phenyl]-2-(1-methyl propyl)-3H-1,2,4-triazole -3- one.
Molecular Formula
C22H27N5O2
Molecular Weight
393.49
Characteristics
Light gray Powder ; sensitive to light
Melting Range
186O to 189OC
Loss on Drying
0.5% max [@ 105O C for 2 hours]
Assay (by HPLC)
99% Min (by% area)
Bulk Packing
Packed in double walled sealed HDPE/PVC bags enclosed in fiber / HDPE drums
Drums
25 / 50 Kgs.
Storage
Store in cool dry place