KETOCONAZOLE

4

KETOCONAZOLE
CAS : 65277-42-1
Chemical Name
cis-1Acetyl-4 [4[[2-(2,4 dichlorophenyl)-2-(1H-imidazole-1-yl methyl)-1,3-dioxolan-4-yl] methoxy] phenyl]piperazine.
Molecular Formula
C26H28Cl2N4O4
Molecular Weight
531.44
Characteristics
White / almost white powder, insoluble in water; soluble in methanol, in Methylene chloride; sensitive to light.
Melting Range
Melts between 148OC to 150OC
Specific Optical Rotation
-1.0O & +1.0O [4% soln in methanol w/v @20OC]
Loss on Drying
Not more than 0.5%[@80OC for 4 hours]
Residue on ignition
Not more than 0.1%
Heavy Metals
Not more than 0.002%
Assay on dry basis
Between 98% and 102%
Stability
Five years from Date of Manufacturing.
Bulk Packing
Packed in double walled sealed HDPE/PVC bags enclosed in fiber / HDPE drums
Drums
25 / 50 Kgs.
Storage
Store in cool dry place
Therapeutic Category
Anti-antifungal.
End Uses
Formulations in tablets, ointments & anti dandruff shampoos. In antifungal preparations for animal husbandary. As a fungicide in agro based products.